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Hotels with non-smoking rooms in Defiance

Hillside Cabin on 43 Acres w/ Private Lake & View!

Defiance, MO
9.9

Exceptional

146 reviews
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Parking

Free WiFi

Non-Smoking Rooms

from
$245
/ night

Business friendly

Holiday Inn Express Hotel & Suites St. Louis West-O'Fallon by IHG

O'Fallon, MO
8.2

Very good

1,001 reviews
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Enjoy an indoor pool, complimentary breakfast, and a business center in O'Fallon, Missouri.

Pool

Parking

Pool Indoor

Free Parking

from
$111
/ night


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