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21c Museum Hotel St Louis

$205
/ night

Avg. for October

21c Museum Hotel St Louis - Image 1
21c Museum Hotel St Louis - Room
21c Museum Hotel St Louis - Room
21c Museum Hotel St Louis - Pool
21c Museum Hotel St Louis - Restaurant

Prices for 21c Museum Hotel St Louis

Select dates to see prices and availability

$205
/ night

Avg. for October

Monthly average prices

Nightly prices at 21c Museum Hotel St Louis average $152 in December, the cheapest month, and $205 in October, the most expensive, based on the last 12 months.

Average nightly price at 21c Museum Hotel St Louis by month, last 12 months (USD)
MonthAverage price
January$169
February$158
March$196
April$171
May$176
June$177
July$194
August$158
September$202
October$205
November$199
December$152

Most expensive: October (~$205)

Cheapest: December (~$152)

About this property

Don't miss out on the many recreational opportunities, including an indoor pool, a steam room, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and a banquet hall.
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  • Parking

  • Restaurant

  • Swimming pool

  • Business Center

  • Room Service

  • Dry Cleaning

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Location

1528 Locust street, Downtown West, St. Louis, Missouri, United States of America

Washington Avenue Historic District (0.1 miles)

City Museum (0.3 miles)

Peabody Opera House (0.3 miles)

Stifel Theatre (0.3 miles)

Enterprise Center (0.4 miles)

Energizer Park (0.4 miles)


Room options

Luxury Suite, 1 King Bed

Room details

1 King Bed

Sleeps 2

549 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Deluxe Room, Accessible

Room details

1 King Bed

Sleeps 2

269 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Luxury Double Room, 2 Queen Beds

Room details

2 Queen Beds

Sleeps 4

423 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Suite, 1 King Bed (21C)

Room details

1 King Bed

Sleeps 2

1119 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Suite, 1 King Bed (Library)

Room details

1 King Bed

Sleeps 2

732 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Deluxe Room, 1 King Bed

Room details

1 King Bed

Sleeps 2

309 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Deluxe Suite, 1 Double Bed, Accessible

Room details

1 Full Bed

Sleeps 2

517 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Room (Bunk Bed)

Room details

1 Bunk Bed

Sleeps 2

237 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Deluxe Room, 1 Double Bed, Accessible

Room details

1 Full Bed

Sleeps 4

388 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Loft, 2 Queen Beds

Room details

2 Queen Beds

Sleeps 4

431 ft²

Air Conditioning
Heating
Wi-Fi (Free)

Guest reviews of 21c Museum Hotel St Louis

What guests think

AI-generated summary based on recent guest reviews

21c Museum Hotel St Louis stands out for its striking art museum setting, excellent pool–spa–gym facilities, and generally friendly staff, while reviews also describe inconsistent cleanliness, service lapses, pricey parking, and a downtown location that can feel deserted or sketchy.

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Facilities

Great

Cleanliness

Inconsistent

Rooms

Mixed

Service

Mixed

Location

Central

Dining

Tasty

Was this helpful?

10

Finn

IAN-logo

2 weeks ago

·

Stayed 1 night

Such a cool and trendy boutique hotel with all the amenities. Beautiful building. Paid parking around d the corner. 20 minutes walk to the Gateway Arch. So nice to get back to the hotel in the evening, have a few drinks at the bar and finish the evening with a visit to the pool area with hot tub, sauna, and steam room as well as the lap pool. Staff were incredible, so friendly and knowledgeable. Kristos and all the other bartenders were super friendly and made us some great cocktails. Would definitely recommend to friends and family and would stay again if we were back in the area.
Such a cool and trendy boutique hotel with all the amenities. Beautiful building. Paid parking around d the corner. 20 minutes walk to the Gateway Arch. So nice to get back to the hotel in the evening, have a few drinks at the bar and finish the evening with a visit to the pool area with hot tub, sauna, and steam room as well as the lap pool. Staff were incredible, so friendly and knowledgeable. Kristos and all the other bartenders were super friendly and made us some great cocktails. Would definitely recommend to friends and family and would stay again if we were back in the area.

10

Stephanie

IAN-logo

3 weeks ago

·

Stayed 2 nights

Wonderful experience, very unique and so close to so much!
Wonderful experience, very unique and so close to so much!

6

Rochelle

IAN-logo

Sep 16, 2026

·

Stayed 3 nights

Interesting concept, but poorly executed. Unfortunately, this did not feel like a true 4-star hotel experience. The location can be convenient if you are visiting the Gateway Arch or attending an event downtown, and for us it worked well because we could walk to the AC/DC concert. Otherwise, there is not much happening immediately around the hotel, and the area did not feel nearly as welcoming or comfortable as other parts of St. Louis. If location had not been so important for this trip, we likely would have changed hotels after the first night and stayed closer to the Kingside Diner/Central West End area, which felt much more lively, cozy, and comfortable for walking around. The biggest disappointment was the lack of attention to detail and maintenance. The AC filter in our room was extremely dirty and looked long overdue for replacement. There were also broken fixtures/supports and issues with the bathroom door. Those are the kinds of things I would not expect to encounter at a hotel positioning itself as a 4-star property. Service also lacked the warmth and attentiveness that normally distinguish a higher-end hotel experience. The bar has a fun concept, but the food felt overpriced for what was delivered. The complimentary bourbon shot is also a clever marketing idea, although calling what was served a “shot” was generous - it was closer to half of one.
Interesting concept, but poorly executed. Unfortunately, this did not feel like a true 4-star hotel experience. The location can be convenient if you are visiting the Gateway Arch or attending an event downtown, and for us it worked well because we could walk to the AC/DC concert. Otherwise, there is not much happening immediately around the hotel, and the area did not feel nearly as welcoming or comfortable as other parts of St. Louis. If location had not been so important for this trip, we likely would have changed hotels after the first night and stayed closer to the Kingside Diner/Central West End area, which felt much more lively, cozy, and comfortable for walking around. The biggest disappointment was the lack of attention to detail and maintenance. The AC filter in our room was extremely dirty and looked long overdue for replacement. There were also broken fixtures/supports and issues with the bathroom door. Those are the kinds of things I would not expect to encounter at a hotel positioning itself as a 4-star property. Service also lacked the warmth and attentiveness that normally distinguish a higher-end hotel experience. The bar has a fun concept, but the food felt overpriced for what was delivered. The complimentary bourbon shot is also a clever marketing idea, although calling what was served a “shot” was generous - it was closer to half of one.

10

Guillaume

IAN-logo

Sep 15, 2026

·

Stayed 1 night

Great location, spacious room.
Great location, spacious room.

10

Jarod

IAN-logo

Sep 14, 2026

·

Stayed 2 nights

Nice room, super cozy bed, and very close to a lot of things downtown. Restaurant was fine. TV streaming didn't work, no ice machines small complaints. Otherwise great stay and loved our choice.
Nice room, super cozy bed, and very close to a lot of things downtown. Restaurant was fine. TV streaming didn't work, no ice machines small complaints. Otherwise great stay and loved our choice.

Property Policies

Check-in instructions

Everything you need to know for a smooth check-in.

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Check-in

Check-out

From 16:00 to 11:00

Before 11:00


Good to know

Additional policies and info about this property.

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Optional extras

Additional paid services you can request.

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FAQs about 21c Museum Hotel St Louis

Is parking available at the hotel?

Valet parking is available at the hotel for a fee of USD 50 per day, which includes in/out privileges. Reservations are not required for parking.


What type of breakfast is offered and what are the serving hours?

Cooked-to-order breakfasts are available daily from 6:30 AM to 1:00 PM for a fee ranging from approximately USD 10 to 25 per person.


Are pets allowed at the hotel?

The hotel allows pets with a fee of USD 100 per accommodation, per stay. Service animals are exempt from this fee.


What are the check-in and check-out times?

Standard check-in time is at 4:00 PM and check-out time is at 11:00 AM. Early or late check-in/check-out may be available upon request, but additional charges may apply.

What accessibility features does the hotel offer for guests with disabilities?

The hotel features limited wheelchair accessibility, including step-free entrances and wheelchair-accessible facilities in public areas. However, specific details about room accessibility are not provided.


Where is the hotel located in relation to key attractions?

The hotel is centrally located in St. Louis, within a 10-minute walk of St. Louis Union Station and City Museum. It is approximately 0.4 miles from Enterprise Center and 0.7 miles from America's Center Convention Complex.


Does the hotel have a swimming pool?

Yes, the hotel features an indoor swimming pool. Specific operational hours are not provided, but it is available for guests to enjoy year-round.


What are the hotel's policies regarding children?

Children are welcome at the hotel. There is no minimum age requirement for children to stay for free.


Have a question?

Instant AI responses are based on hotel information


Considering this hotel for your St. Louis trip?

What do room rates at 21c Museum Hotel St Louis usually run in the near term?

Over the next 60–90 days, room rates at 21c Museum Hotel St Louis in St Louis typically land around $148 a night for two guests, ranging from $140 to $216 on peak dates.


When is the quietest time to visit 21c Museum Hotel St Louis?

August is the quietest month to stay at 21c Museum Hotel St Louis in St Louis, while November is the busiest. If you prefer fewer crowds and easier availability, aim for late summer.


Which month has the lowest rates at 21c Museum Hotel St Louis?

December is the cheapest month to stay at 21c Museum Hotel St Louis in St Louis, averaging $181 a night; October is the priciest at $243. December’s lower rates come even though the quietest month for crowds is August.

What’s nearby and who does 21c Museum Hotel St Louis suit?

Set in St Louis City County, 21c Museum Hotel St Louis is steps from the Washington Avenue Historic District and the City Museum, with easy access to the Peabody Opera House and St. Louis Union Station. The hotel’s mix of Luxury and Business themes makes it a fit for couples and business travellers exploring downtown attractions.


How do this hotel’s rates compare with other nearby hotels?

21c Museum Hotel St Louis is cheaper than 7 of 19 comparable hotels nearby, with a typical median of $186 a night versus about $171 for peers.


How does the nightly price at 21c Museum Hotel St Louis in St. Louis compare to recent weeks?

The current price at 21c Museum Hotel St Louis in St. Louis is $181 per night for 2 guests, which is typical for this hotel: within 10% of its $197 average over the last 60 days. Most nights over that period fell between $149 and $426.

Prices for upcoming dates

October 2026
November 2026

Cheaper

Pricier

Average nightly price across deals, with taxes & fees.

Prices in USD for 2 guests, updated daily.



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